Are UAD-2 cards supported on PCIe x4 or x16 slots?

can we install PCIE x16 graphics card in PCIE pcie 2 0 x16 slot
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pcie 30 x1 slot PCIe x 1 for RTX 4080 Super 30423052 B-Key x 1 + MicroSIM Slot 2230 E-Key x 1 TPM, TPM Onbaord Indicator, System LED x 1, HDD Activity x 1